CBN Cannabinoid

What Are the Cannabinol (CBN) Cannabinoid Effects?

Cannabinol (CBN) is one of the lesser known cannabinoids whose primary effect is sedation. This article examines the benefits of CBN, the conditions it may treat and how it works. I will also list the strains that have appreciable amounts of CBN.

THCA turns into CBNA which becomes CBN when exposed to heat or oxygen, known as oxidation. It can be non-psychoactive or lightly psychoactive, depending on its stage of degradation. If you leave your flower around for a long time or in a container which is not air-tight, the result is cannabis with higher amounts of CBN. This reduces its THC content, but that is not a bad thing. The result is changes in the chemical and therapeutic properties of your medicine.

Here’s How It Works 

CBN primarily binds to CB2 receptors which is thought to alleviate pain. Its effects are significantly increased when combined with THC. Without pain, it is much easier to get to sleep and to stay asleep which may account for its reported effectiveness as a sleep aid. CBN has been well documented as inducing drowsiness with relaxing soporific effects.

CBN forms in smaller quantities and more slowly than CBD. CBN is much more difficult to extract and produce than CBD. Like all other cannabinoids in cannabis, CBN works more effectively in conjunction with other cannabinoids, particularly with CBD and THC.

Benefits of CBN

  • Anti-inflammatory
  • Anti-bacterial
  • Analgesic
  • Anti-insomnia
  • Anti-convulsive
  • Appetite Stimulant
  • Antiproliferative
  • Anxiolytic

Conditions That CBN May Treat

  1. Bone Tissue Growth and Fracture Healing
    Studies suggest that CBN may stimulate the growth of bone tissue as a result of an indirect procurement of mesenchymal stem cells from the surround bone marrow. These stem cells are not only able to turn into blood cells, but they are also able to turn into bone cells, expediting fracture healing.
  2. Reduce Skin Cell Overgrowth
    This is important for those who suffer from psoriasis, inflammatory condition where there is an abnormally fast regeneration of skin cells. CBN may help to regulate the production of skin cells.
  3. Burns
    As an anti-inflammatory and an analgesic, CBN in tandem with CBD, may act to reduce pain from burns by binding with TRPV2 receptors (high-threshold thermosensors.)
  4. Treat MRSA
    A 2008 Italian study suggested that CBN, along with CBG, THC, CBD and CBC may effectively treat MRSA.
  5. ALS
    A 2005 mice study by Weydt, Hong, et al., published in the journal, Amyotrophic Lateral Sclerosis, suggests that CBN may be able to delay the onset of symptoms of ALS.

Strains With Higher Concentrations of CBN

Indica strains typically have higher concentrations of CBN, although there are also sativas containing significant amounts. Although it is rare for the CBN content in any strain to exceed 1%, only very small doses are required to have a sedating and calming effect. Research indicates that 5mg of CBN works as well as 10mg of diazepam or similar pharmaceuticals.

Blackberry          0.398
Bubble Gum         0.386
Durban Poison       0.363
Lemon Kush         0. 49
Sonoma Coma       0.372
Strawberry Cough    0.362
Super Green Crack    0.788 

CBN is now available in capsules, transdermal patches, drinks, oils, sublingual strips, topicals, salves, ointments and edibles. Avoid products that isolate the CBN compound and do not contain other cannabinoids.

Sources:
leafly.com, What is CBB and What Are the Benefits of This Cannabinoid? Bailey Rahn, May 12, 2015
analyticalcannabis.com, Beyond CBD: Exploring The Health Benefits of CBN in Cannabis, George Mouratidis, Feb 12, 2019
hightimes.com, What is CBN (Cannabinol) And What Does It Do? Ab Hanna, Jan 8, 2018
potbiotics.com, Strains